What is anal cancer?

  • A rare cancer that starts in the tissues of the anus.

  • Often linked to persistent infection with certain types of human papillomavirus (HPV).

  • Preventable and treatable when detected early.

Talking with your family and friends

  • Use simple language to explain the diagnosis and what it means.

  • Share how they can support you—practical help, rides, meals, or just listening.

  • Remember, it’s okay to set boundaries about what you do or don’t want to discuss.

Caring for yourself or a loved one during treatment

  • Manage side effects with your care team’s guidance (skin care, fatigue, bowel changes).

  • Keep track of symptoms and report them early.

  • Accept help—this is not the time to “do it all.”

  • Stay connected with loved ones for emotional support.

Living with—and beyond—anal cancer.

Here’s to the survivors and the thrivers, the recently-diagnosed and all the people who love them.

Healing

  • Healing is more than physical—emotional, sexual, and spiritual recovery are important.

  • Explore therapies like counseling, pelvic floor therapy, or mindfulness practices.

  • Reconnect with activities and relationships that bring joy.

  • Give yourself permission to move forward at your own pace.

Cancer has the ability to make the best of us panic-stricken and fearful or it can become the turning point in our lives, helping us to transform into courageous, grateful, and more alive spiritual beings
— Theresa Mayhew - Kicking Cancer in the Butt

Symptoms

  • Anorectal bleeding or blood on toilet paper.

  • Pain, itching, or lumps around the anus.

  • Changes in bowel habits or stool shape.

  • Unexplained weight loss or fatigue.

Treatment options

  • Chemoradiation (combination of chemotherapy and radiation therapy).

  • Surgery, in some cases.

  • Participation in clinical trials for new therapies.

  • Supportive care to manage symptoms and side effects.

Caring for yourself or a loved one after treatment

  • Attend regular follow-up visits and screenings.

  • Practice self-care: exercise, balanced meals, and stress reduction.

  • Be patient—healing takes time, both physically and emotionally.

  • Reach out for survivorship resources or support groups.

Diagnosis

  • Physical exam and medical history.

  • Anal Pap and HPV test to check for abnormal cells and high-risk HPV types.

  • High-resolution anoscopy (HRA)-guided biopsy to identify abnormal cells (dysplasia), similary to cervical coloposcopy.

  • Imaging tests (CT, MRI, PET) to see if cancer has spread.

  • Multidisciplinary care team: primary care, nurse navigators, medical, radiation and surgical oncologists, dietitian, physical, occupational & pelvic floor therapists, mental health, social worker, palliative care and more.

Caring for yourself or a loved one before treatment

  • Get informed about the treatment plan and expected side effects.

  • Arrange support at home (meals, childcare, transportation).

  • Focus on nutrition, hydration, and rest to prepare your body.

  • Address emotional health—counseling, support groups, or journaling.

Let’s make anal cancer a hot topic.

Few words make people more uncomfortable than 'anus' and 'cancer'. But silence around these topics has real consequences: delayed diagnoses, missed prevention, social isolation and worse outcomes for those living with anal cancer. Breaking the stigma starts with open conversation—conversation that can save lives.